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Stanford's 2026 AI Index cites a study that pitted Microsoft's AI Diagnostic Orchestrator, paired with OpenAI's o3 reasoning model, against 21 practicing physicians with five to twenty years of experience working unaided on diagnostically challenging New England Journal of Medicine cases. The AI system's accuracy reached 85.5%, versus about 20% for the unaided physicians

The Stanford HAI AI Index 2026 report cites a study where Microsoft's AI Diagnostic Orchestrator, paired with OpenAI's o3 reasoning model, was tested on challenging cases from the New England Journal of Medicine. The AI system achieved 85.5% accuracy. This was compared to approximately 20% accuracy among 21 practicing physicians with five to 20 years of clinical experience working under comparable conditions.

Verified 2026-09-28

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On hard medical puzzles AI can outperform doctors working alone, though real clinics are messier than tests.

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